A Novel Injectable Polymeric Biomaterial Poly(propylene fumarate-co-caprolactone) with Controllable Properties for Bone and Nerve Regenerations
نویسندگان
چکیده
Recently a novel crosslinkable and biodegradable copolymer poly(propylene fumarateco-caprolactone) (PPF-co-PCL) has been synthesized in our lab (Figure 1). By varying copolymer composition, controllable physical properties can be achieved to satisfy various needs in tissue engineering, particularly, bone and nerve regenerations. The physical properties of the copolymers have been extensively investigated and the glass transition temperature (Tg) decreases progressively with increasing the PCL composition. Therefore, the biodegradation rate and mechanical properties can be well modulated by the different molecular structure, copolymer composition, and crosslinking density.
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